Peptide Database

Peptide NameMouse beta-defensin-14

Function Ontology

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Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC193H343N67O55S6

DescriptionStandard

        SLQRSYCKIRSGRCAVLSCLPKEEQIGTCSLRGRKCCRKKK
    

Molecular Weight4674.59 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)9.40

Net Charge (pH 7.4) 9.09

Charge Density (pH 7.0) 0.2293

GRAVY Index-0.68

Hydrophobic Moment 0.51

Boman Index-0.39

Instability Index67.62

Aliphatic Index 66.59

Aromaticity 0.0244

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2048.44

LogP -25.37

H-bond Donors 82.0

H-bond Acceptors 71.0

Rotatable Bonds 167.0

Heavy Atoms 321.0

Ring Count 2.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0027189 VERIFIED: YES

Provenance & Taxonomy

OrganismPteropus alecto [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)