Peptide Database

Peptide Name3m (monomer Atrial natriuretic peptide- Fc )

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Standard StatusStandard

Sequence Length42 amino acids

Chemical FormulaC178H283N63O58S4

DescriptionStandard

        SLRRSSCFGGRMDRIGAQSGLGCNSFRYGSGGSGGFCREGIN
    

Molecular Weight4361.80 Da

Isoelectric Point (pI)9.79

Net Charge (pH 7.0)3.43

Net Charge (pH 7.4) 3.18

Charge Density (pH 7.0) 0.0817

GRAVY Index-0.47

Hydrophobic Moment 0.60

Boman Index-0.10

Instability Index60.42

Aliphatic Index 39.52

Aromaticity 0.0952

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1993.53

LogP -31.47

H-bond Donors 77.0

H-bond Acceptors 66.0

Rotatable Bonds 148.0

Heavy Atoms 303.0

Ring Count 4.0

Amide Bonds 44.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0399938 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyNatriuretic peptide

Tax ID32630

Structure & Mods

Configbranched peptide architecture [Branched]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermNone

C-TermFc region

Disulfide7-23

Other ModsComposite modified token region

Bio-Activity Profile

Function

Natriuretic Vasodilator

MethodELISA

Half-LifeFemale Wistar rats Plasma, in vivo; 16200 s