Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC555H885N149O169S4

DescriptionStandard

        PDLSGYEKFGLGNVKYNISRIHVTAVELPSASISLIPGTGIKLVIRNASLTINMNWNIRTWMFKDSGRSTAYISKVFVTALFSTSLDNMNHTSISFTSCQTTSGDIDIKLNGKS
    

Molecular Weight12477.12 Da

Isoelectric Point (pI)9.48

Net Charge (pH 7.0)4.12

Net Charge (pH 7.4) 3.93

Charge Density (pH 7.0) 0.0362

GRAVY Index-0.01

Hydrophobic Moment 0.57

Boman Index0.10

Instability Index18.72

Aliphatic Index 91.49

Aromaticity 0.0877

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5137.63

LogP -58.43

H-bond Donors 184.0

H-bond Acceptors 179.0

Rotatable Bonds 415.0

Heavy Atoms 877.0

Ring Count 17.0

Amide Bonds 123.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0177954 VERIFIED: NO

Provenance & Taxonomy

OrganismCiccaba nigrolineata [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria