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MYP_036868
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Basic Information
Temporin B
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C83H121N19O16
Standard
Sequence
FVQWFSKFLGRIL
Physicochemical Analysis
1640.97 Da
11.00
1.76
1.55
0.1353
0.82
0.70
0.34
24.05
112.31
0.3077
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
579.55
-0.26
21.0
18.0
52.0
118.0
5.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0390539 VERIFIED: YES
Provenance & Taxonomy
Rana temporaria [Animal]
Temporin
8400
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial
PMID9022710;18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9022710/
RECORD: Rec_0418694 VERIFIED: YES
Provenance & Taxonomy
Rana temporaria [Animal]
Temporin
8407
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
C-terminal amidated
Bio-Activity Profile
Antimicrobial Antifungal Anticancer Antiparasitic
Bacillus megaterium
PaperTemporins, antimicrobial peptides from the European red frog Rana temporaria.
RECORD: Rec_0423639 VERIFIED: YES
Provenance & Taxonomy
Rana temporaria [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumanii ATCC 17978
4 μg/mL
MIC
PMID31358802 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31358802/
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