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MYP_036868
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Basic Information
Temporin B
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C83H121N19O16
Standard
Sequence
FVQWFSKFLGRIL
Physicochemical Analysis
1640.97 Da
11.00
1.76
1.55
0.1353
0.82
0.70
0.34
24.05
112.31
0.3077
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
579.55
-0.26
21.0
18.0
52.0
118.0
5.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0315093 VERIFIED: YES
Provenance & Taxonomy
Rana temporaria [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
B. megaterium
PMID9022710 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9022710/
RECORD: Rec_0320087 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0321453 VERIFIED: YES
Provenance & Taxonomy
Rana temporaria [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumanii AYE
4 μg/mL
MIC
PMID31358802 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31358802/
RECORD: Rec_0326375 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
12 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/22974815/ PMID22974815 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22974815/
RECORD: Rec_0327215 VERIFIED: NO
Provenance & Taxonomy
Rana temporaria [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial
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