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MYP_036868
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Basic Information
Temporin B
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C83H121N19O16
Standard
Sequence
FVQWFSKFLGRIL
Physicochemical Analysis
1640.97 Da
11.00
1.76
1.55
0.1353
0.82
0.70
0.34
24.05
112.31
0.3077
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
579.55
-0.26
21.0
18.0
52.0
118.0
5.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0001547 VERIFIED: YES
Provenance & Taxonomy
Rana temporaria [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae M6
16 μg/mL
MIC
PMID31358802 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31358802/
RECORD: Rec_0002177 VERIFIED: YES
Provenance & Taxonomy
Rana temporaria [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa PAO1 128
16 μg/mL
MIC
PMID31358802 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31358802/
RECORD: Rec_0016134 VERIFIED: YES
Provenance & Taxonomy
Rana temporaria [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Epidemic methicillin resistant Staphylococcus aureus-16
4 μg/mL
MIC
PMID31358802 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31358802/
RECORD: Rec_0023387 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
2 μM
LC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/19635516/ PMID19635516 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19635516/
RECORD: Rec_0034662 VERIFIED: YES
Provenance & Taxonomy
Rana temporaria [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Epidemic methicillin resistant Staphylococcus aureus-15
4 μg/mL
MIC
PMID31358802 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31358802/
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