Peptide Database

Peptide NameInterferon-induced protein with tetratricopeptide repeats 2

Function Ontology

Antiviral

Antiviral ▸ Anti-Flavivirus ▸ Anti-West Nile virus

Antiviral ▸ Anti-POXVIRUS

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Standard StatusStandard

Sequence Length472 amino acids

Chemical FormulaC2450H3818N674O719S25

DescriptionStandard

        MSTTSKESLVCNLRQLKCHFTWNLIAEDESLDEFEDRVFNKDEFQNSEFKATMCNILAYVKHCRGLNEAALQCLGEAEGFIQQQHPDQVEIRSLVTWGNYAWVYYHMGQFSKAQAYLDKVKQVCKKFSSPYRIENPALDCEEGWARLKCTKNQNERVKVCFQKALEKDPKNPEFTSGWAIAFYRLDDWPARNYCIDSLEQAIQLSPDNTYVKVLLALKLDAVHVHKNQAMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNAYVHYYMGCCYRSKVHHMLNRREMVFSGDRKKLEELIQLAVNHLRKAEEIKEMLEYSCSFLADLYIIAKKYDEADYYFQKELSKDLPPGPKQLLHLRYGNFQFFQMKRQDKAIYHYMEGVKIKKKTIPQKKMREKLQRIALRRLHEDESDSEALHILAFLQENGGGQQADKDSERGVDSANQVPSASLDEDGAEY
    

Molecular Weight55020.23 Da

Isoelectric Point (pI)7.18

Net Charge (pH 7.0)0.66

Net Charge (pH 7.4) -0.66

Charge Density (pH 7.0) 0.0014

GRAVY Index-0.60

Hydrophobic Moment 0.76

Boman Index-0.11

Instability Index43.95

Aliphatic Index 78.79

Aromaticity 0.1038

Extinction Coeff. Reduced 68760.00

Extinction Coeff. Oxidized 69635.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0350368 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyIFIT

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral RNA cap-sensing restriction factor Anti-WNV Anti-coronavirus Anti-POXVIRUS

TargetWest Nile virus, coronavirus, poxvirus