Peptide Database

Peptide NameDermaseptin-PC, DM-PC

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC131H223N37O37S

DescriptionStandard

        ALWKSILKNVGKAAGKAVLNAVTDMVNQ
    

Molecular Weight2940.46 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)2.79

Net Charge (pH 7.4) 2.60

Charge Density (pH 7.0) 0.0998

GRAVY Index0.26

Hydrophobic Moment 0.68

Boman Index0.15

Instability Index7.12

Aliphatic Index 115.00

Aromaticity 0.0357

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1219.01

LogP -11.61

H-bond Donors 41.0

H-bond Acceptors 41.0

Rotatable Bonds 101.0

Heavy Atoms 206.0

Ring Count 2.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0349841 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa coelestis [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetKlebsiella pneumoniae ATCC 43816

Activity64 μM

MethodMBC

RECORD: Rec_0420008 VERIFIED: YES