Peptide Database

Peptide NamePancrelipase

Function Ontology

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC135H198N38O38

DescriptionStandard

        QYSPNTQQGRTSIVHLFEWRWVDI
    

Molecular Weight2961.25 Da

Isoelectric Point (pI)6.75

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0062

GRAVY Index-0.72

Hydrophobic Moment 0.33

Boman Index-0.05

Instability Index30.36

Aliphatic Index 72.92

Aromaticity 0.1667

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1256.00

LogP -10.97

H-bond Donors 44.0

H-bond Acceptors 39.0

Rotatable Bonds 92.0

Heavy Atoms 211.0

Ring Count 8.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0014527 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]; Bos taurus [Animal]

FamilyEnzyme

Tax ID9823;9913

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme replacement

Half-LifePancrelipase is not significantly absorbed from the gastrointestinal tract and acts locally, so limination half-life is not relevant