Peptide Database

Peptide NameToxin with colicin-like bacteriocin tRNase domain (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length680 amino acids

Chemical FormulaC3211H5149N927O1014S21

DescriptionStandard

        MGASLSLGKTLSVHGEWATHKRRTYVPTRQTAQFMRFGTPGHPVDELVIYGSQLKGVMGTGTIRKLTLVDKADTHAQDGASWNASVSLKDLGKTGWDAVSSVGAGVKGGDSSKVVDGKAEFKCDGVEILEPIERITAETYDRRYGVNATKHFTSAGDAAAAYAPAYSGRLELGEDSVGFELPNVMFHEKTETTSQQITRRDAEQAALEAQRQREAAQRAADAAEELQRNALKAICDQFEAENPTLVKDLIAKEAAEAEAQRAAEAQRQREAAQRAAEAAQDTELQKEKINEALMNILTPGQLQESVTDAKEAERVKIREASIALIRRLRPEVTDAEAQQLRDMYDRKSGRLMNAAMEAYRGSTAENVLHRVSEVIGTVTGELIKGAALAPLDPYETREEWAERSREYDEMKGPMQYLGDGLHATTKEVGHYGLGMSEENAETFATLAMDGVNIATAGRMLKPGVKPALNAAGTVLKGAGGAATAMFETLLSLLRDLEVKAPPAIATPLEIATAGEARAAAAAQPAAVAEAAVSSRPLSLPYIEGGRYVPGKAMMSFELTNPPVLMRGTHNSAGKVPLEVAQKLSGKEFSSFDAFRSEFWKTMAESSYAKEFKSADIARMQKGNAPIVHLEQSLGSRITYELHHRTPIHDGGPVYDLSNLLIVTPKYHKEILSKQSHYGVK
    

Molecular Weight73637.20 Da

Isoelectric Point (pI)5.92

Net Charge (pH 7.0)-9.97

Net Charge (pH 7.4) -11.24

Charge Density (pH 7.0) -0.0147

GRAVY Index-0.42

Hydrophobic Moment 0.67

Boman Index-0.04

Instability Index35.25

Aliphatic Index 77.65

Aromaticity 0.0574

Extinction Coeff. Reduced 55810.00

Extinction Coeff. Oxidized 55935.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0130064 VERIFIED: NO

Provenance & Taxonomy

OrganismCandidatus Paracaedibacteraceae [Bacterium]

FamilyBacteriocin

Tax ID1777752

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Hydrolase Non-hemolytic Non-ribosomal