Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length464 amino acids

Chemical FormulaC2281H3632N614O654S15

DescriptionStandard

        MGVRSLLVASTVLALGLALSGATNPGFVVRITQAGLDYAKQHGVAVLEKELAQLKLQDISGESRIPVLGKVRYEISRLNLRNFQLPYSQISLVPNEGLQVSISNAFAELDGNWRVKLRILRHHGSFNLNVEHVYIKTTLKLGRDDSGKPTVDISACSTSISNVRVRFSGKLSWLYNLFSKTIASKFKENLEGKVCETLRSSVRRYLQPYLQTVPVTANIDAVAGIDYSLTAAPVATAQFLNVDLKGECFSRAQHTPVPFTPPALAVPPEHDRMVYFGVSSYFFNTASFAYHTAGALIFEITDTMIPKDIEFRLNTSTFAAFLPQLDEMYPNMPMKFSLSAPSAPFLSIGTNGVSLQPVVDIQAYAIYPNGNLAPLFLLGLTGNVSATADVQSGRMVGSLAVGRMKLTLKHSNVGTGTFKVKMMQSIMNVVASSILLPRLNGNNLLGGMGLLEQTPLRSLHQFVN
    

Molecular Weight50601.93 Da

Isoelectric Point (pI)9.47

Net Charge (pH 7.0)11.28

Net Charge (pH 7.4) 10.48

Charge Density (pH 7.0) 0.0243

GRAVY Index0.12

Hydrophobic Moment 0.70

Boman Index0.13

Instability Index33.58

Aliphatic Index 100.22

Aromaticity 0.0841

Extinction Coeff. Reduced 31860.00

Extinction Coeff. Oxidized 31985.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0047663 VERIFIED: NO

Provenance & Taxonomy

OrganismCairina moschata domestica (Muscovy Duck (domestic type)) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria