Peptide Database

Peptide NameTositumomab

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length240 amino acids

Chemical FormulaC1141H1746N294O356S10

DescriptionStandard

        QAYLQQSGAELVRPGASVKMSCKASGYTFTSYNMHWVKQTPRQGLEWIGAIYPGNGDTSYNQKFKGKATLTVDKSSSTAYMQLSSLTSEDSAVYFCARVVYYSNSYWYFDVWGTGTTVTVSGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKAEPKSCDKTHTCPPCPAPELLGGPSV
    

Molecular Weight25598.48 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)5.04

Net Charge (pH 7.4) 4.47

Charge Density (pH 7.0) 0.0210

GRAVY Index-0.22

Hydrophobic Moment 0.59

Boman Index0.09

Instability Index45.70

Aliphatic Index 64.12

Aromaticity 0.1083

Extinction Coeff. Reduced 48360.00

Extinction Coeff. Oxidized 48735.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0110381 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]; Cricetulus griseus [Animal]

FamilyMonoclonal antibody

Tax ID10090;10029

Structure & Mods

Configlinear multidomain protein biologic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer Monoclonal antibody Antimicrobial Antibacterial

Half-Life0.8 h (mammalian reticulocytes, in vitro)

PaperPubMed-linked source references: PMID:16179960; PMID:15071612; PMID:27195659; PMID:25568316; PMID:22531442; PMID:21355777; PMID:21225019; PMID:19649342; PMID:19455266 PMID16179960;15071612;27195659;25568316;22531442;21355777;21225019;19649342;19455266 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16179960/