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MYP_036617
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Basic Information
Arenicin-2
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
21 amino acids
C128H197N41O25S2
Standard
Sequence
RWCVYAYVRIRGVLVRYRRCW
Physicochemical Analysis
2774.32 Da
10.85
5.74
5.50
0.2732
-0.06
0.57
-0.21
63.76
97.14
0.2381
15470.00
15595.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1108.99
-4.81
47.0
33.0
85.0
196.0
7.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0214024 VERIFIED: NO
Provenance & Taxonomy
Insecta [Animal]
50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0261064 VERIFIED: NO
Provenance & Taxonomy
Arenicola marina [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-20
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli, Listeria monocytogenes and fungus, Candida albicans
RECORD: Rec_0267263 VERIFIED: YES
Provenance & Taxonomy
Arenicola marina [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
3-20
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Listeria monocytogenes EGD
PaperPubMed PMID: 15527787 | PubMed PMID: 17935487 | PubMed PMID: 17585874 PMID15527787;17935487;17585874 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15527787/
RECORD: Rec_0305443 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 76.2%, T 9.5%, C 14.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Antifungal Anti-Gram-positive Cytotoxic Anti-Gram-negative
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0329734 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Arenicola marina [Synthetic]
Arenicin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-20
Bio-Activity Profile
Antimicrobial Antifungal
Gram-negative Escherichia coli ML-35p
4 μg/mL
MIC
PaperPurification and primary structure of two isoforms of arenicin, a novel antimicrobial peptide from marine polychaeta, Arenicola marina
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