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MYP_036614
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Basic Information
Galleria defensin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Standard
43 amino acids
C198H297N59O64S6
Standard
Sequence
DTLIGSCVWGATNYTSDCNAECKRRGYKGGHCGSFLNVNCWCE
Physicochemical Analysis
4720.22 Da
6.73
-0.20
-0.56
-0.0047
-0.40
0.55
-0.02
35.15
45.35
0.1163
13980.00
14355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2005.02
-25.75
77.0
71.0
151.0
327.0
8.0
46.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0033261 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
Defensin
7137
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antifungal
A. niger
2.1 μM
MIC
PaperPurification, cDNA cloning and expression of an insect defensin from the great wax moth, Galleria mellonella
RECORD: Rec_0038034 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
Defensin
7130
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
7-32, 18-40, 22-42
Bio-Activity Profile
Antimicrobial Antifungal
Fusarium oxysporum
16.9 μM
MIC
PMID17194500;14728668 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17194500/
RECORD: Rec_0049185 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
Defensin
7137
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antifungal
PaperInsect Mol Biol 2004; 13: 65-72 | http://www.ncbi.nlm.nih.gov/pubmed/14728668 PMID14728668 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14728668/
RECORD: Rec_0052012 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
Defensin
7137
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antifungal
Z. marxianus, P. tannophilus, Candida albicans, C. fructus
8.5 μM
MIC
PaperPurification, cDNA cloning and expression of an insect defensin from the great wax moth, Galleria mellonella
RECORD: Rec_0071489 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
Defensin
7130
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
7-32, 18-40, 22-42
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
8.5 μM
MIC
PMID17194500;14728668 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17194500/
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