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MYP_036564
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Basic Information
Temporin-SHf
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
8 amino acids
C57H77N11O10
Standard
Sequence
FFFLSRIF
Physicochemical Analysis
1076.29 Da
9.75
0.76
0.56
0.0950
1.77
0.55
0.56
32.83
97.50
0.5000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
349.15
1.11
13.0
11.0
32.0
78.0
4.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0105527 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharica [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli ATCC 35218
200 μM
MIC
PMID20308076 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20308076/
RECORD: Rec_0120423 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharica [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Fungus
200 μM
MIC
PMID20308076 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20308076/
RECORD: Rec_0127804 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharicus [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
25 μM
MIC
PMID20308076 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20308076/
RECORD: Rec_0135625 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharicus [Animal]
Temporin
70019
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Bacillus subtilis 168
100 μM
MIC
PaperMishra B, Lushnikova T, Golla RM, Wang X, Wang G. Design and surface immobilization of short anti-biofilm peptides. Acta Biomater. 2017;49:316-328. doi:10.1016/j.actbio.2016.11.061 PMID27915018 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27915018/
RECORD: Rec_0157077 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharica [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Yeasts: Candida albicans ATCC 90028
50 μM
MIC
PMID20308076 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20308076/
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