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MYP_036564
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Basic Information
Temporin-SHf
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
8 amino acids
C57H77N11O10
Standard
Sequence
FFFLSRIF
Physicochemical Analysis
1076.29 Da
9.75
0.76
0.56
0.0950
1.77
0.55
0.56
32.83
97.50
0.5000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
349.15
1.11
13.0
11.0
32.0
78.0
4.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0346066 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharica [Animal]
Temporin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis ATCC 29212
50 μM
MIC
PMID20308076 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20308076/
RECORD: Rec_0351062 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharica [Animal]
Temporin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
25 μM
MIC
PMID20308076 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20308076/
RECORD: Rec_0352419 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharica [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Pseudomonas aeruginosa ATCC 27853
200 μM
MIC
PMID20308076 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20308076/
RECORD: Rec_0363805 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharicus [Animal]
Temporin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Hemolytic Cytolytic
Erythrocytes
200.0 μM
HC50
PaperF. Abbassi et al. / The Journal of Biological Chemistry 285 (2010) 16880-16892. Temporin-SHf, a New Type of Phe-rich and Hydrophobic Ultrashort Antimicrobial Peptide Evidence URLhttps://www.uniprot.org/uniprotkb/D4YWD1/entry
RECORD: Rec_0364390 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharica [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
parapsilosis ATCC 22019
50 μM
MIC
PMID20308076 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20308076/
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