Peptide Database

Peptide NameLt-F11Q (Derived from Lt)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC76H134N26O18

DescriptionStandard

        FKRIVQRIKDQLR
    

Molecular Weight1700.04 Da

Isoelectric Point (pI)11.72

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.2892

GRAVY Index-0.92

Hydrophobic Moment 0.90

Boman Index-0.55

Instability Index24.50

Aliphatic Index 112.31

Aromaticity 0.0769

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 773.74

LogP -5.69

H-bond Donors 28.0

H-bond Acceptors 22.0

Rotatable Bonds 62.0

Heavy Atoms 120.0

Ring Count 1.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0353890 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

TargetHuman erythrocytes (10% Hemolysis at >1280 μM

Activity1280 μM

MethodHemolysis

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