MYP_036531
Kappa-actitoxin-Ael2a (Kappa-AITX-Ael2a) (Toxin APETx1)
Annotation / Sequence feature
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Nuclear export signal
Antimicrobial
Antimicrobial
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Antibiotic activity
Membrane / Ion-channel modulation
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Ion channel inhibition
Toxicity / Safety
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Negative safety assay result
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Non-hemolytic
Venom / Toxin
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General toxin
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Toxin
Venom / Toxin
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Toxin
Standard
42 amino acids
C203H295N49O59S6
Standard
GTTCYCGKTIGIYWFGTKTCPSNRGYTGSCGYFLGICCYPVD
4558.20 Da
8.30
1.70
1.39
0.0404
0.08
0.30
0.21
7.96
44.05
0.1905
12950.00
13325.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1711.95
-18.15
68.0
67.0
136.0
317.0
11.0
42.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0051959
VERIFIED: YES
Provenance & Taxonomy
Anthopleura elegantissima [Animal]
Sea anemone type 3 (BDS) potassium channel toxin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibiotic
Toxin
Non-hemolytic
No Target Organism Found
RECORD: Rec_0100324
VERIFIED: YES
Provenance & Taxonomy
Anthopleura elegantissima [Animal]
sea anemone type 3 (BDS) potassium channel toxin family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
4-37; 6-30; 20-38
Bio-Activity Profile
Toxin
Venom
sea anemone type 3 (BDS) potassium channel toxin family
Ion channel inhibitor
Pathogenesis-associated
RECORD: Rec_0162730
VERIFIED: NO
Provenance & Taxonomy
Anthopleura elegantissima [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
4-37; 6-30; 20-38
Bio-Activity Profile
Toxin
KCNH2, HERG1, KCNH6, HERG2, KCNH7, HERG3