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MYP_036501
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Basic Information
P5-NT2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C83H158N20O15
Standard
Sequence
LLKKPLLKKLLKKL
Physicochemical Analysis
1676.27 Da
10.70
5.75
5.54
0.4110
0.11
0.63
-0.10
-26.42
195.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
588.95
1.30
20.0
21.0
64.0
118.0
1.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0044369 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
1.56 μM
MIC
PMID31363941 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31363941/
RECORD: Rec_0137301 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 25923
1.56 μM
MIC
PaperMechanism of action of antimicrobial peptide P5 truncations against Pseudomonas aeruginosa and Staphylococcus aureus.
RECORD: Rec_0203687 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii KCTC 2508
12.5 μM
MIC
PMID31363941 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31363941/
RECORD: Rec_0279222 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
3.13 μM
MIC
PMID31363941 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31363941/
RECORD: Rec_0296287 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
Mice RBCs [No hemolysis upto 100 microM]
100 μM
Hemolysis
PMID31363941 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31363941/
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