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MYP_036486
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Basic Information
R. prolixus defensin A (RprDefA; insect defensin; Insects, animals)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Insecticidal/Pest control ▸ Insecticidal activity
Standard
43 amino acids
C200H322N70O53S6
Standard
Sequence
ATCDLFSFRSKWVTPNHAACAAHCLLRGNRGGRCKGTICHCRK
Physicochemical Analysis
4747.52 Da
9.69
7.00
6.56
0.1627
-0.29
0.58
-0.13
38.30
54.65
0.0698
5500.00
5875.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1990.75
-24.53
79.0
69.0
154.0
329.0
8.0
44.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0162096 VERIFIED: YES
Provenance & Taxonomy
Rhodnius prolixus [Animal]
RprDefA
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperInsect Biochem Mol Biol. 2003 Apr;33(4):439-47 | http://www.ncbi.nlm.nih.gov/pubmed/12650692 PMID12650692 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12650692/
RECORD: Rec_0231458 VERIFIED: YES
Provenance & Taxonomy
Rhodnius prolixus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Micrococcus luteus
PMID12650692 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12650692/
RECORD: Rec_0334873 VERIFIED: YES
Provenance & Taxonomy
Rhodnius prolixus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
PMID12650692 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12650692/
RECORD: Rec_0368608 VERIFIED: YES
Provenance & Taxonomy
Rhodnius prolixus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperIsolation and characterization of a novel insect defensin from Rhodnius prolixus, a vector of Chagas disease.
RECORD: Rec_0398139 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
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