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MYP_036465
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Basic Information
Antimicrobial peptide UyCT1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C78H113N19O18
Standard
Sequence
GFWGKLWEGVKNAI
Physicochemical Analysis
1604.85 Da
8.59
0.76
0.55
0.0544
-0.05
0.56
0.28
4.61
83.57
0.2143
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
605.63
-1.95
21.0
19.0
51.0
115.0
5.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0207845 VERIFIED: YES
Provenance & Taxonomy
Urodacus yaschenkoi [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0226660 VERIFIED: YES
Provenance & Taxonomy
Urodacus yaschenkoi [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes 81% lysis
50 μM
Hemolysis
PMID23182832 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23182832/
RECORD: Rec_0228634 VERIFIED: YES
Provenance & Taxonomy
Urodacus yaschenkoi [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 9027
10 μM
MIC
PMID23182832 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23182832/
RECORD: Rec_0243386 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0247889 VERIFIED: YES
Provenance & Taxonomy
Urodacus yaschenkoi [Animal]
UyC
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic
PaperToxicon. 2013 Mar 1;63:44-54. | http://www.ncbi.nlm.nih.gov/pubmed/23182832 PMID23182832 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23182832/
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