MYP_036440
Bradykinin-potentiating peptide 12a
Anticancer
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Cytotoxic anticancer activity
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Cytotoxic
Cardiovascular
Enzyme modulation
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Enzyme inhibition
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ACE inhibition
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ACE inhibitory
Membrane / Ion-channel modulation
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Ion channel modulation
Regulatory peptide
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Biological modulation
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
Venom / Toxin
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General toxin
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Toxic
Standard
12 amino acids
C69H97N19O15
Standard
QGWAWPRPQIPP
1432.63 Da
9.75
0.76
0.56
0.0633
-1.15
0.16
0.03
46.39
40.83
0.1667
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
527.92
-2.30
16.0
16.0
35.0
103.0
8.0
13.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0013102
VERIFIED: YES
Provenance & Taxonomy
Bothrops jararaca [Animal]
Bradykinin-potentiating peptide 12a
8724
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Pyroglutamate
Bio-Activity Profile
Cardiovascular
Enzyme modulation
Ion channel modulation
ACE inhibitory
Mammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour
RECORD: Rec_0297912
VERIFIED: YES
Provenance & Taxonomy
Bothrops jararaca [Animal]
Bradykinin-potentiating peptide 12a
8724
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Pyroglutamate
Bio-Activity Profile
Cardiovascular
Enzyme modulation
Ion channel modulation
ACE inhibitory
angiotensin-converting enzyme
Mammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour
RECORD: Rec_0325594
VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 66.7%, C 33.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic
Cytotoxic