Peptide Database

Peptide NameDefensin-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length59 amino acids

Chemical FormulaC263H434N86O90S7

DescriptionStandard

        EEYEPLEHADIEERADRQRRVTCDLLSIKGVAEHSACAANCLSMGKAGGRCENGVCLCR
    

Molecular Weight6465.24 Da

Isoelectric Point (pI)5.24

Net Charge (pH 7.0)-3.03

Net Charge (pH 7.4) -3.40

Charge Density (pH 7.0) -0.0513

GRAVY Index-0.48

Hydrophobic Moment 0.49

Boman Index-0.17

Instability Index47.12

Aliphatic Index 72.88

Aromaticity 0.0169

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2863.85

LogP -34.62

H-bond Donors 106.0

H-bond Acceptors 96.0

Rotatable Bonds 221.0

Heavy Atoms 446.0

Ring Count 4.0

Amide Bonds 61.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0053227 VERIFIED: NO

Provenance & Taxonomy

OrganismBombus lapidarius [Animal]

FamilyDefensin

Tax ID30192

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal