Peptide Database

Peptide Name2'-5'-oligoadenylate synthase 1A

Function Ontology

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Standard StatusStandard

Sequence Length367 amino acids

Chemical FormulaC1937H2972N518O539S9

DescriptionStandard

        MEHGLRSIPAWTLDKFIEDYLLPDTTFGADVKSAVNVVCDFLKERCFQGAAHPVRVSKVVKGGSSGKGTTLKGKSDADLVVFLNNLTSFEDQLNRRGEFIKEIKKQLYEVQHERRFRVKFEVQSSWWPNARSLSFKLSAPHLHQEVEFDVLPAFDVLGHVNTSSKPDPRIYAILIEECTSLGKDGEFSTCFTELQRNFLKQRPTKLKSLIRLVKHWYQLCKEKLGKPLPPQYALELLTVFAWEQGNGCYEFNTAQGFRTVLELVINYQHLRIYWTKYYDFQHQEVSKYLHRQLRKARPVILDPADPTGNVAGGNPEGWRRLAEEADVWLWYPCFIKKDGSRVSSWDVPTVVPVPFEQVEENWTCILL
    

Molecular Weight42428.05 Da

Isoelectric Point (pI)8.30

Net Charge (pH 7.0)3.35

Net Charge (pH 7.4) 2.40

Charge Density (pH 7.0) 0.0091

GRAVY Index-0.38

Hydrophobic Moment 0.80

Boman Index-0.02

Instability Index39.16

Aliphatic Index 84.66

Aromaticity 0.1199

Extinction Coeff. Reduced 78380.00

Extinction Coeff. Oxidized 78880.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0027869 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyOAS

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsS-geranylgeranylation Cys364

Bio-Activity Profile

Function

Antiviral Replication inhibitor Translation regulator RNA-sensing effector Protein degradation regulator

TargetSARS-CoV-2