Peptide Database

Peptide NameMacromomycin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length145 amino acids

Chemical FormulaC623H1026N174O210S4

DescriptionStandard

        MTATKKLGLIARLGATAAIATGLALATQSSAMAAPTVSVSPVSGLSDGQTVAVSASGLTPNTVFHIGQCAQVEAQKFGCNKSTSKDVTTNAQGEINTSLVVRSSFEAVVSADGPVWGTVDAKTTQTQVVVLSDAGEGGGQAITFK
    

Molecular Weight14442.11 Da

Isoelectric Point (pI)6.54

Net Charge (pH 7.0)-0.42

Net Charge (pH 7.4) -0.74

Charge Density (pH 7.0) -0.0029

GRAVY Index0.22

Hydrophobic Moment 0.50

Boman Index0.17

Instability Index22.19

Aliphatic Index 86.14

Aromaticity 0.0345

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6132.43

LogP -85.16

H-bond Donors 214.0

H-bond Acceptors 215.0

Rotatable Bonds 476.0

Heavy Atoms 1011.0

Ring Count 11.0

Amide Bonds 157.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0426404 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptomyces sp. 13-12-16 [Bacterium]

FamilyNeocarzinostatin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal