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MYP_036377
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Basic Information
Hill-Def 2a
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
40 amino acids
C179H294N62O48S6
Standard
Sequence
ATCDLLSPFKVGHAACAAHCIARGKRGGWCDKRAVCNCRK
Physicochemical Analysis
4275.03 Da
9.38
5.91
5.52
0.1477
-0.13
0.54
-0.10
49.30
61.25
0.0500
5500.00
5875.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1772.41
-20.83
70.0
62.0
140.0
295.0
6.0
40.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0280887 VERIFIED: YES
Provenance & Taxonomy
Hermetia illucens [Animal]
Defensin
343691
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-36
3-36
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
MRC-5 SV2
32 μM
IC50
PMID34985302 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34985302/
RECORD: Rec_0293395 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 25.0%, E 20.0%, T 32.5%, C 22.5% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-positive
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0371808 VERIFIED: YES
Provenance & Taxonomy
Hermetia illucens [Animal]
Defensin
343691
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-36
3-36
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 9027
32 μM
IC50
PMID34985302 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34985302/
RECORD: Rec_0383550 VERIFIED: YES
Provenance & Taxonomy
Hermetia illucens [Animal]
DL
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PaperDev Comp Immunol. 2015 Sep;52(1):98-106. | http://www.ncbi.nlm.nih.gov/pubmed/25956195 PMID25956195 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25956195/
RECORD: Rec_0392790 VERIFIED: YES
Provenance & Taxonomy
Hermetia illucens [Animal]
Defensin
343691
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923a
0.01 μM
MIC
PMID28935900 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28935900/
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