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MYP_036377
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Basic Information
Hill-Def 2a
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
40 amino acids
C179H294N62O48S6
Standard
Sequence
ATCDLLSPFKVGHAACAAHCIARGKRGGWCDKRAVCNCRK
Physicochemical Analysis
4275.03 Da
9.38
5.91
5.52
0.1477
-0.13
0.54
-0.10
49.30
61.25
0.0500
5500.00
5875.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1772.41
-20.83
70.0
62.0
140.0
295.0
6.0
40.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0162215 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0163705 VERIFIED: YES
Provenance & Taxonomy
Hermetia illucens [Animal]
Defensin
343691
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 6538
0.19 μM
IC50
PMID34985302 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34985302/
RECORD: Rec_0185775 VERIFIED: YES
Provenance & Taxonomy
Hermetia illucens [Animal]
Defensin
343691
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
A. fumigatus B42928
32 μM
IC50
PMID34985302 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34985302/
RECORD: Rec_0189316 VERIFIED: YES
Provenance & Taxonomy
Hermetia illucens [Animal]
Defensin
343691
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus CICC546c
0.47 μM
MIC
PMID28935900 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28935900/
RECORD: Rec_0196372 VERIFIED: YES
Provenance & Taxonomy
Hermetia illucens [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S. suis CVCC 3928
3.75 μM
MIC
PaperPurification and characterization of a novel antibacterial peptide from black soldier fly (Hermetia illucens) larvae
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