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MYP_036354
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Basic Information
Unnamed
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Pneumovirus ▸ Anti-RSV
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
5 amino acids
C29H57N11O6S
Standard
Sequence
LMRIR
Physicochemical Analysis
687.90 Da
12.00
1.76
1.56
0.3520
0.24
0.49
-0.40
-7.08
156.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
303.52
-1.29
12.0
9.0
24.0
47.0
0.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0246333 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-RSV Replication inhibition
Porcine reproductive and respiratory syndrome virus (PRRSV) | MARC-145 cells
716.4 μM
IC50
Mammalian: 5.5 h; Yeast: 3 min; E. coli: 2 min
PaperAntiviral activity of phage display selected peptides against Porcine reproductive and respiratory syndrome virus in vitro. | Liu K, Feng X, Ma Z, Luo C, Zhou B, Cao R, Huang L, Miao D, Pang R, He D, Lian X, Chen P. | Virology. 2012 Oct 10;432(1):73-80. | DOI:10.1016/j.virol.2012.05.010 | PMID:22743126 PMID22743126 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22743126/
RECORD: Rec_0256934 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Library-derived peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Replication inhibitor
Porcine reproductive and respiratory syndrome virus (Replication); MARC-145
716.4193 μM
MTT assay
PaperAntiviral activity of phage display selected peptides against Porcine reproductive and respiratory syndrome virus in vitro. | Liu K, Feng X, Ma Z, Luo C, Zhou B, Cao R, Huang L, Miao D, Pang R, He D, Lian X, Chen P. | Virology. 2012 | PMID:22743126 PMID22743126 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22743126/
RECORD: Rec_0273064 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Porcine reproductive and respiratory syndrome virus(PRRSV):inhibition of PRRSV replication in MARC-145 cells
716.4193 μM
IC50
PaperPubMed PMID: 22743126 PMID22743126 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22743126/
RECORD: Rec_0295236 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PaperPubMed PMID: 22743126 PMID22743126 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22743126/
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