Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-Pneumovirus ▸ Anti-RSV

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length5 amino acids

Chemical FormulaC29H57N11O6S

DescriptionStandard

        LMRIR
    

Molecular Weight687.90 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.56

Charge Density (pH 7.0) 0.3520

GRAVY Index0.24

Hydrophobic Moment 0.49

Boman Index-0.40

Instability Index-7.08

Aliphatic Index 156.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 303.52

LogP -1.29

H-bond Donors 12.0

H-bond Acceptors 9.0

Rotatable Bonds 24.0

Heavy Atoms 47.0

Ring Count 0.0

Amide Bonds 4.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0246333 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilySynthetic peptide

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-Term-

C-Term-

Bio-Activity Profile

Function

Antiviral Anti-RSV Replication inhibition

TargetPorcine reproductive and respiratory syndrome virus (PRRSV) | MARC-145 cells

Activity716.4 μM

MethodIC50

Half-LifeMammalian: 5.5 h; Yeast: 3 min; E. coli: 2 min

PaperAntiviral activity of phage display selected peptides against Porcine reproductive and respiratory syndrome virus in vitro. | Liu K, Feng X, Ma Z, Luo C, Zhou B, Cao R, Huang L, Miao D, Pang R, He D, Lian X, Chen P. | Virology. 2012 Oct 10;432(1):73-80. | DOI:10.1016/j.virol.2012.05.010 | PMID:22743126 PMID22743126 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22743126/

RECORD: Rec_0256934 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyLibrary-derived peptide

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Replication inhibitor

TargetPorcine reproductive and respiratory syndrome virus (PRRSV); MARC-145 cells

Activity716.4193 μM

MethodMTT assay

PaperAntiviral activity of phage display selected peptides against Porcine reproductive and respiratory syndrome virus in vitro. | Liu K, Feng X, Ma Z, Luo C, Zhou B, Cao R, Huang L, Miao D, Pang R, He D, Lian X, Chen P. | Virology. 2012 | PMID:22743126 PMID22743126 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22743126/

RECORD: Rec_0273064 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-Term-

C-Term-

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetPorcine reproductive and respiratory syndrome virus (PRRSV); MARC-145 cells

Activity716.4193 μM

MethodIC50

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