Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length227 amino acids

Chemical FormulaC1135H1742N264O344S10

DescriptionStandard

        TCTVPMPIDDLAEVDYSLNTFPAVFRQFIDLDLKGIVYPAGNYTGSTCVAAPFTIPDQSDSMLHLAFSEHFFQTSSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPVVSLEQDSFTVEIQGSMEVLAVLPDSTTQLLFTMNIAANTSIALNVFDQKLVGSLCLNRLQFSLAHSNVGFFEISLLENILSYILQTEVIPSANGK
    

Molecular Weight24910.18 Da

Isoelectric Point (pI)4.17

Net Charge (pH 7.0)-16.35

Net Charge (pH 7.4) -16.80

Charge Density (pH 7.0) -0.0720

GRAVY Index0.38

Hydrophobic Moment 0.63

Boman Index0.26

Instability Index42.71

Aliphatic Index 100.09

Aromaticity 0.1145

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13660.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0182005 VERIFIED: NO

Provenance & Taxonomy

OrganismPedionomus torquatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria