Peptide Database

Peptide Namenatriuretic peptide PpNP-b

Function Ontology

Antimicrobial

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC162H266N54O54S3

DescriptionStandard

        SGSKTANIGDGCFGVRLDHIGTTSGMGCGRPRPKPTPGGS
    

Molecular Weight3930.37 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)2.53

Net Charge (pH 7.4) 2.24

Charge Density (pH 7.0) 0.0632

GRAVY Index-0.57

Hydrophobic Moment 0.31

Boman Index-0.03

Instability Index38.54

Aliphatic Index 39.00

Aromaticity 0.0250

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1709.01

LogP -27.36

H-bond Donors 62.0

H-bond Acceptors 61.0

Rotatable Bonds 125.0

Heavy Atoms 273.0

Ring Count 6.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0005943 VERIFIED: YES

Provenance & Taxonomy

OrganismPseudechis porphyriacus [Animal]

Familynatriuretic peptide PpNP

Tax ID8671

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-28

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0068826 VERIFIED: NO