Peptide Database

Peptide NameJEV(1968-1975)

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-Flavivirus ▸ Anti-Japanese encephalitis virus

Antiviral ▸ Anti-Flavivirus ▸ Anti-West Nile virus

Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Enzyme modulation ▸ Enzyme inhibition ▸ Helicase inhibition

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC35H58N14O14

DescriptionStandard

        RNPNQVGD
    

Molecular Weight898.92 Da

Isoelectric Point (pI)6.09

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0295

GRAVY Index-2.04

Hydrophobic Moment 0.68

Boman Index-0.52

Instability Index-8.89

Aliphatic Index 36.25

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 486.70

LogP -7.66

H-bond Donors 15.0

H-bond Acceptors 14.0

Rotatable Bonds 28.0

Heavy Atoms 63.0

Ring Count 1.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0377049 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetHepatitis C virus (HCV): inhibition of HCV helicase activity

Activity500 μM

MethodIC50

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