Peptide Database

Peptide NametRNA3(Ser)-specific nuclease WapA (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length865 amino acids

Chemical FormulaC4255H6549N1271O1382S14

DescriptionStandard

        MQYAYDAAGNVLKQAILGTDGECLESSTRYDLKDRATHRTNPAGGVTRYLYDRNDRLRKEISPYGYEPENDDGAGAAYTYDSRGNRLRTTNALGEVVQELSYNLRNQPVIQKDTFGNRTELSYELDGKIKDVRRSGNHQRTLQQYEYNARGQITGVVDGNRNPISYDVDSWGRITGIGFVDGVKEGYEYTPAGQVSRTIDGNGNAVQYRYNSLGKVSERIDQLGDTETFRYDEEGNLSLHIDRDGRQLQRACNVFGQPVYEKATDAEGKHTNISTWHYDSLGRVTRAVCDGKSYEYIYDAYGNLKEKRSNGKRLVSYTHDRAGQITEIRDPTGVSTRYEYDILGRRSRIFNDDGLEVRYGYDALNRIRHIRYGNGVETACTYDGDGNIRTLETRAGENVLLSFAYRYDGNGNRTAKTGTQAALGGITAGNNALDLSYNYDVRGQLLEERRNGASVCYAYDKAGNRIRKTDAQGETRYLYNEKNQLTAEESPVDRKQFSYDRQGGIIEEKNAAGIRLFSYNSRHQQTRVETETGNVQENRYDAEGLRFELLENGRRTSFVYHNGELLQEEGREEQGTSYHLGAGMEAFRRGQELSYYHRDEQLSTALVTDGHRNVQNSYQYDAFGMSLGTTEKLNNRIRYTGQQYDDVTGQYYLRARYYNPVAGRFMQEDVYQGDGLNLYAYCGNNPVVYDDPSGYERKACPPQGKISESVDGSGSNTTATERRNSPGVVEGNGRNTSKMMYGTDKNAGVIPKEIADKLREKQYNNFDEFRNDFWKAVAETDYANEFLINGDPKNYYRMKNGGAPLVVSNQAINGSFTYQLHHIIPINQGGSVYSVDNLVVVTPRYHAEILIPEVHGYNGFKQFFR
    

Molecular Weight98069.11 Da

Isoelectric Point (pI)5.94

Net Charge (pH 7.0)-10.04

Net Charge (pH 7.4) -11.46

Charge Density (pH 7.0) -0.0116

GRAVY Index-0.92

Hydrophobic Moment 0.89

Boman Index-0.18

Instability Index35.45

Aliphatic Index 63.58

Aromaticity 0.1075

Extinction Coeff. Reduced 119310.00

Extinction Coeff. Oxidized 119685.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0281201 VERIFIED: NO

Provenance & Taxonomy

Organismuncultured Clostridium sp [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal