Peptide Database

Peptide NameIFN-α7

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length166 amino acids

Chemical FormulaC874H1364N238O257S9

DescriptionStandard

        CDLPQTHSLRNRRALILLAQMGRISPFSCLKDRHEFRFPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLEACVIQEVGVEETPLMNEDFILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTNLKKGLRRKD
    

Molecular Weight19606.21 Da

Isoelectric Point (pI)5.87

Net Charge (pH 7.0)-2.89

Net Charge (pH 7.4) -3.40

Charge Density (pH 7.0) -0.0174

GRAVY Index-0.43

Hydrophobic Moment 0.73

Boman Index-0.08

Instability Index60.60

Aliphatic Index 81.08

Aromaticity 0.1084

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17210.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8077.63

LogP -77.35

H-bond Donors 283.0

H-bond Acceptors 267.0

Rotatable Bonds 666.0

Heavy Atoms 1378.0

Ring Count 29.0

Amide Bonds 182.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0088535 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsPredicted disulphide bond formation between cysteine residues at positions 1 and 99, and 29 and 139

Bio-Activity Profile

Function

Receptor agonist Signaling peptide

TargetInterferon-α/β receptor (Human)