Peptide Database

Peptide Namemahafacyclin A

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antiparasitic ▸ Antimalarial

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC34H55N7O9

DescriptionStandard

        GTILGVF
    

Molecular Weight705.84 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0343

GRAVY Index1.97

Hydrophobic Moment 0.28

Boman Index0.80

Instability Index23.96

Aliphatic Index 152.86

Aromaticity 0.1429

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 258.15

LogP -1.06

H-bond Donors 9.0

H-bond Acceptors 9.0

Rotatable Bonds 21.0

Heavy Atoms 50.0

Ring Count 1.0

Amide Bonds 6.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0192836 VERIFIED: YES

Provenance & Taxonomy

OrganismJatropha mahafalensis [Plant]

FamilyOrbitide

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer Antimalarial Cytotoxic

TargetP. falciparum

Activity16 μM

MethodIC50

RECORD: Rec_0235310 VERIFIED: NO