Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length111 amino acids

Chemical FormulaC524H817N141O165S16

DescriptionStandard

        MKTFSVAVAVAVVLTFICVQQSSANVCFSEQELEEPMSMDYPAAAHEEASVDSWKMLYNSRHKRGIKCRFCCGCCTPVSVEFAAGSEDSCSHNHSVLTNCMSQTMCEIILF
    

Molecular Weight12244.98 Da

Isoelectric Point (pI)5.20

Net Charge (pH 7.0)-5.23

Net Charge (pH 7.4) -5.82

Charge Density (pH 7.0) -0.0471

GRAVY Index0.16

Hydrophobic Moment 0.45

Boman Index0.11

Instability Index72.06

Aliphatic Index 69.37

Aromaticity 0.0811

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 9105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4875.39

LogP -54.40

H-bond Donors 178.0

H-bond Acceptors 180.0

Rotatable Bonds 401.0

Heavy Atoms 846.0

Ring Count 17.0

Amide Bonds 118.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0325369 VERIFIED: NO

Provenance & Taxonomy

OrganismOreochromis niloticus [Animal]

FamilyHepcidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal