Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length141 amino acids

Chemical FormulaC685H1094N190O195S4

DescriptionStandard

        PTVLPAAHEPMLLLAVTEFVANSAAFTYFTAGALRRNISSDMLPRRFPLQLRTKSLGLFSPELQERYPDQPMELHLSARQQPLLSCRPDALHGALFGSAEAFVVLPNATRVPAFLLNIDANVTGKPTITGNRLGGTVSLTG
    

Molecular Weight15239.43 Da

Isoelectric Point (pI)9.18

Net Charge (pH 7.0)2.23

Net Charge (pH 7.4) 1.98

Charge Density (pH 7.0) 0.0158

GRAVY Index0.09

Hydrophobic Moment 0.57

Boman Index0.11

Instability Index51.68

Aliphatic Index 96.95

Aromaticity 0.0709

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6066.98

LogP -60.23

H-bond Donors 209.0

H-bond Acceptors 204.0

Rotatable Bonds 484.0

Heavy Atoms 1074.0

Ring Count 26.0

Amide Bonds 151.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0160834 VERIFIED: NO

Provenance & Taxonomy

OrganismThalassarche chlororhynchos (Atlantic yellow-nosed albatross) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria