Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC366H586N100O88S8

DescriptionStandard

        MKLLLLTLTVLLLLSQLTPGGTQRCWNLYGKCRHRCSKKERVYVYCLNSKMCCVKPKYQPKERWWPF
    

Molecular Weight8051.71 Da

Isoelectric Point (pI)9.82

Net Charge (pH 7.0)10.52

Net Charge (pH 7.4) 10.15

Charge Density (pH 7.0) 0.1570

GRAVY Index-0.27

Hydrophobic Moment 0.48

Boman Index-0.07

Instability Index33.73

Aliphatic Index 87.16

Aromaticity 0.1194

Extinction Coeff. Reduced 22460.00

Extinction Coeff. Oxidized 22835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3055.05

LogP -20.12

H-bond Donors 115.0

H-bond Acceptors 108.0

Rotatable Bonds 265.0

Heavy Atoms 562.0

Ring Count 16.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0107104 VERIFIED: NO

Provenance & Taxonomy

OrganismPiliocolobus tephrosceles [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0275766 VERIFIED: NO

Provenance & Taxonomy

OrganismColobus angolensis palliatus [Animal]

FamilyDefensin

Tax ID336983

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence