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MYP_035957
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Basic Information
GcLEAP-2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Standard
41 amino acids
C199H304N60O58S6
Standard
Sequence
MTPLWRIMGTKPHGAYCQNHYECSTGICRKGHCSYSQPINS
Physicochemical Analysis
4657.30 Da
8.86
2.72
2.29
0.0663
-0.67
0.44
-0.05
27.26
40.49
0.0976
9970.00
10220.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1890.58
-22.23
70.0
70.0
146.0
323.0
11.0
44.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0007231 VERIFIED: YES
Provenance & Taxonomy
Ctenopharyngodon idella [Animal]
LEAP-2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID19716607 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19716607/
RECORD: Rec_0011722 VERIFIED: YES
Provenance & Taxonomy
Chinese grass carp [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperMolecular cloning and expression analysis of the liver-expressed antimicrobial peptide 2 (LEAP-2) gene in grass carp
RECORD: Rec_0022202 VERIFIED: NO
Provenance & Taxonomy
Chinese grass [Animal]; Actinopterygii [Animal]
33208; 7898
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0107940 VERIFIED: YES
Provenance & Taxonomy
Ctenopharyngodon idella [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0242816 VERIFIED: NO
Provenance & Taxonomy
Ctenopharyngodon idella [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
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