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MYP_035922
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C88H140N26O21S
Standard
Sequence
WLNALLHHGLNCAKGVLA
Physicochemical Analysis
1930.28 Da
8.24
0.92
0.60
0.0513
0.67
0.42
0.36
4.22
141.11
0.0556
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
743.37
-4.69
26.0
25.0
61.0
136.0
4.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0272740 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Toxic Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0280929 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
25 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/12067731/ PMID12067731 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12067731/
RECORD: Rec_0302367 VERIFIED: YES
Provenance & Taxonomy
Halocynthia aurantium [Animal]
Halocidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
No hemolytic activity towards human erythrocytes
Hemolysis
PMID12067731 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12067731/
RECORD: Rec_0328433 VERIFIED: YES
Provenance & Taxonomy
Halocynthia aurantium [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0382812 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Human erythrocytes
100 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/12878508/ PMID12878508 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12878508/
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