‹ ›
MYP_035898
← PREVIOUS NEXT → BACK
Basic Information
Caerulein
Antimicrobial
Cardiovascular
Cardiovascular ▸ Blood pressure regulation ▸ Blood pressure lowering / Hypotensive activity
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Standard
10 amino acids
C58H75N13O19S
Standard
Sequence
QQDYTGWMDF
Physicochemical Analysis
1290.36 Da
4.05
-2.24
-2.44
-0.2239
-1.26
0.26
-0.02
59.02
0.00
0.3000
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
542.25
-4.08
18.0
18.0
39.0
91.0
4.0
11.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0247226 VERIFIED: YES
Provenance & Taxonomy
Litoria xanthomera [Animal]
Caerulein
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Fall of the blood pressure Contraction of the gall bladder Stimulating acid secretion of the stomach Increasing the pancreatic juice secretion
PaperA. Anastasi et al. / British Journal of Pharmacology 38 (1970) 221-228. Presence of caerulein in extracts of the skin of Leptodactylus pentadactylus labyrinthicus and of Xenopus laevis Evidence URLhttps://www.uniprot.org/uniprotkb/P56264/entry
RECORD: Rec_0264237 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Caerulein
8355
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
4:Sulfotyrosine
Bio-Activity Profile
Hormone Endocrine
Mammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Caerulein (Xenopus laevis): PMID 5413288 PMID5413288 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5413288/
RECORD: Rec_0279393 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Caerulein
8355
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Pyroglutamate
Amidation
4:Sulfotyrosine
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator
Mammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Caerulein (Xenopus laevis): PMID 5413288 PMID5413288 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5413288/
RECORD: Rec_0316281 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0407575 VERIFIED: YES
Provenance & Taxonomy
Litoria rothii [Animal]
Caerulein
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Fall of the blood pressure Contraction of the gall bladder Stimulating acid secretion of the stomach Increasing the pancreatic juice secretion
PaperA. Anastasi et al. / British Journal of Pharmacology 38 (1970) 221-228. Presence of caerulein in extracts of the skin of Leptodactylus pentadactylus labyrinthicus and of Xenopus laevis Evidence URLhttps://www.uniprot.org/uniprotkb/P86506/entry
FIRST PREV 1 2 3 NEXT LAST
Showing 5 records on this page · Page 2 of 3