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MYP_035878
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Basic Information
Lysozyme C (EC 3.2.1.17)
Annotation / Structural annotation
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme
Antimicrobial ▸ Antifungal
Binding / Molecular interaction ▸ Binding activity
Binding / Molecular interaction ▸ Metal-binding peptide
Enzyme / Catalytic activity ▸ Hydrolase
Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase
Immunology ▸ Adverse immune reactivity ▸ Allergenicity ▸ Allergen
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
147 amino acids
C705H1116N214O204S12
Standard
Sequence
MRSLLILVLCFLPLAALGKVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL
Physicochemical Analysis
16238.49 Da
9.36
8.50
8.08
0.0578
-0.15
0.56
-0.00
19.86
81.70
0.0884
37470.00
37970.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
6800.95
-76.84
250.0
226.0
534.0
1135.0
23.0
163.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0100916 VERIFIED: NO
Provenance & Taxonomy
Gallus lafayettii [Animal]
Glycosyl hydrolase 22
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic
Evidence URLhttps://www.uniprot.org/uniprotkb/B8YK77/entry
RECORD: Rec_0167427 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Alpha-lactalbumin
9031;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Allergen Lactose Synthesis Structural Cell Wall Remodeling Calcium Binding Antimicrobial
PaperExons encode functional and structural units of chicken lysozyme. Proc. Natl. Acad. Sci. U.S.A. 77:5759-5763 PMID6934509 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6934509/
RECORD: Rec_0188342 VERIFIED: NO
Provenance & Taxonomy
Gallus sonneratii [Animal]
Glycosyl hydrolase 22
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic
Evidence URLhttps://www.uniprot.org/uniprotkb/B8YK75/entry
RECORD: Rec_0218682 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Glycosyl hydrolase 22
9031
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic
No Target Organism Found
PMID6934509;11788708;15592404;19845599;893412;14063294;383714;14301784;5857373;3325501;22044478;5891407;1255711;1255720;1712773;3349024;9220986 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6934509/
RECORD: Rec_0415304 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
9031
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Micrococcus luteus A270 (MIC 0.01 ?.02 µM)
PaperEvidence of an Antimicrobial Peptide Signature Encrypted in HECT E3 Ubiquitin Ligases