Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length86 amino acids

Chemical FormulaC412H634N118O122S13

DescriptionStandard

        MKTFSVAVAVAVVLTFVCLQQSSAVPVNEQEQELEQPVNYAYQEMPVESWQMPYSSRHKRHSNAAGCRFCCGCCPNMHGCGVCCRF
    

Molecular Weight9609.00 Da

Isoelectric Point (pI)6.78

Net Charge (pH 7.0)-0.32

Net Charge (pH 7.4) -0.83

Charge Density (pH 7.0) -0.0037

GRAVY Index-0.06

Hydrophobic Moment 0.45

Boman Index0.05

Instability Index91.42

Aliphatic Index 58.84

Aromaticity 0.0930

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3834.89

LogP -42.46

H-bond Donors 138.0

H-bond Acceptors 138.0

Rotatable Bonds 306.0

Heavy Atoms 665.0

Ring Count 17.0

Amide Bonds 96.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0143141 VERIFIED: NO

Provenance & Taxonomy

OrganismLeiognathus equula [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence