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MYP_035851
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Basic Information
Subtilosin A1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
35 amino acids
C154H238N38O45S3
Standard
Sequence
NKGCAICSIGAACLVDGPIPDFEIAGATGLFGLWG
Physicochemical Analysis
3437.96 Da
4.05
-2.27
-2.52
-0.0647
0.84
0.29
0.44
24.71
100.57
0.0857
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1272.40
-11.42
45.0
46.0
106.0
240.0
6.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0149267 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Bacteriocin
1423
Structure & Mods
thioether-constrained cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
Thioether bridges between Cys4 and Phe31,Cys7 and Thr28,Cys13 and Phe22
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus cereus
40 μM
MIC
PaperPubMed PMID: 19633086 PMID19633086 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19633086/
RECORD: Rec_0186517 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Bacillus anthracis
2.56 μM
MIC
PMID19633086 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19633086/
RECORD: Rec_0199989 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Like Bacillus subtilis
100 μM
MIC
PaperIsolation of a variant of subtilosin A with hemolytic activity.
RECORD: Rec_0214005 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Bacteriocin
1423
Structure & Mods
thioether-constrained cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
Thioether bridges between Cys4 and Phe31,Cys7 and Thr28,Cys13 and Phe22
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus thuringiensis
40 μM
MIC
PaperPubMed PMID: 19633086 PMID19633086 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19633086/
RECORD: Rec_0214706 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus carnosus
16 μM
MIC
PMID19633086 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19633086/
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