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MYP_035851
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Basic Information
Subtilosin A1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
35 amino acids
C154H238N38O45S3
Standard
Sequence
NKGCAICSIGAACLVDGPIPDFEIAGATGLFGLWG
Physicochemical Analysis
3437.96 Da
4.05
-2.27
-2.52
-0.0647
0.84
0.29
0.44
24.71
100.57
0.0857
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1272.40
-11.42
45.0
46.0
106.0
240.0
6.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0056398 VERIFIED: NO
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Structure & Mods
backbone-cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic
RECORD: Rec_0079837 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Streptococcus pyogenes
6.4 μM
MIC
PMID19633086 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19633086/
RECORD: Rec_0083725 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Bacillus cereus, B. thuringiensis
64 μM
MIC
PaperIsolation of a variant of subtilosin A with hemolytic activity.
RECORD: Rec_0104649 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
B. anthracis, Bacillus cereus, B. thuringiensis, Enterococcus faecalis, S. carnosus, Listeria monocytogenes, and S. pyogenes
3-16 μM
MIC
PaperIsolation of a variant of subtilosin A with hemolytic activity.
RECORD: Rec_0109539 VERIFIED: NO
Provenance & Taxonomy
Bacillus subtilis [Bacterium]; Bacteria [Bacterium]
1423; 2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID23638029 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23638029/
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