Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length123 amino acids

Chemical FormulaC620H983N175O167S2

DescriptionStandard

        MVARPYHVVVVLLLLESSARFGEGASNPGVVARITRKGLEYANQYAVATLRKELPAIRLPDFSGSFKIGWFGRVSYNFQSLKIHRFEVRNSDLSLLPGLGIRASLSNNDLSVGGNWKVKKGFM
    

Molecular Weight13624.64 Da

Isoelectric Point (pI)10.38

Net Charge (pH 7.0)8.68

Net Charge (pH 7.4) 8.34

Charge Density (pH 7.0) 0.0706

GRAVY Index0.00

Hydrophobic Moment 0.74

Boman Index0.06

Instability Index21.16

Aliphatic Index 99.02

Aromaticity 0.1057

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 16960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5510.00

LogP -50.39

H-bond Donors 195.0

H-bond Acceptors 180.0

Rotatable Bonds 451.0

Heavy Atoms 964.0

Ring Count 22.0

Amide Bonds 131.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0258214 VERIFIED: NO

Provenance & Taxonomy

OrganismSpermophilus dauricus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence