Peptide Database

Peptide NameUnnamed

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Reproductive neuropeptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC422H654N134O120S

DescriptionStandard

        QHWSHGWYPGGKRASNSPQDPQSALRPPAPSAAQTAHSFRSAALASPEDSVPWEGRTTAGWSLRRKQHLMRTLLSAAGAPRPAAVPIKP
    

Molecular Weight9556.60 Da

Isoelectric Point (pI)11.55

Net Charge (pH 7.0)7.11

Net Charge (pH 7.4) 6.70

Charge Density (pH 7.0) 0.0799

GRAVY Index-0.74

Hydrophobic Moment 0.58

Boman Index-0.09

Instability Index78.51

Aliphatic Index 54.04

Aromaticity 0.0674

Extinction Coeff. Reduced 23490.00

Extinction Coeff. Oxidized 23490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4001.20

LogP -48.63

H-bond Donors 139.0

H-bond Acceptors 132.0

Rotatable Bonds 290.0

Heavy Atoms 677.0

Ring Count 26.0

Amide Bonds 94.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0050099 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0090330 VERIFIED: NO

Provenance & Taxonomy

OrganismTupaia belangeri [Animal]

FamilyProgonadoliberin

Tax ID37347

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0283190 VERIFIED: NO

Provenance & Taxonomy

OrganismTupaia belangeri [Animal]

FamilyGnRH

Tax ID37347

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsGly10 Amidation

Bio-Activity Profile

Function

Hormone Reproductive neuropeptide