Peptide Database

Peptide NameBovine neutrophil Beta-defensin 12 (BNBD-12; cattle, ruminant, mammals; animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC173H284N58O45S6

DescriptionStandard

        GPLSCGRNGGVCIPIRCPVPNRQIGTCFGRPVKCCRSW
    

Molecular Weight4088.86 Da

Isoelectric Point (pI)9.57

Net Charge (pH 7.0)5.70

Net Charge (pH 7.4) 5.41

Charge Density (pH 7.0) 0.1500

GRAVY Index-0.07

Hydrophobic Moment 0.69

Boman Index-0.03

Instability Index59.08

Aliphatic Index 63.95

Aromaticity 0.0526

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1637.34

LogP -19.82

H-bond Donors 63.0

H-bond Acceptors 57.0

Rotatable Bonds 125.0

Heavy Atoms 282.0

Ring Count 8.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0397687 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Tax ID9913

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Disulfide5-34; 12-27; 17-35

Bio-Activity Profile

Function

Antimicrobial Antibacterial