Peptide Database

Peptide NameSLAY-screened peptide P2968

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC118H196N44O22S2

DescriptionStandard

        PCHHLVNKMKKWFVRRRRVR
    

Molecular Weight2647.23 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)8.12

Net Charge (pH 7.4) 7.94

Charge Density (pH 7.0) 0.4060

GRAVY Index-1.15

Hydrophobic Moment 0.66

Boman Index-0.57

Instability Index136.09

Aliphatic Index 63.00

Aromaticity 0.1000

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1106.03

LogP -7.79

H-bond Donors 44.0

H-bond Acceptors 34.0

Rotatable Bonds 90.0

Heavy Atoms 186.0

Ring Count 6.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0318447 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/