Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length55 amino acids

Chemical FormulaC276H439N67O83S6

DescriptionStandard

        METEKYLQVVEDEELEQLVGGAGPGWVETLTKDCPWKQPVACVIIMGQKICKKCY
    

Molecular Weight6216.23 Da

Isoelectric Point (pI)4.69

Net Charge (pH 7.0)-3.53

Net Charge (pH 7.4) -3.82

Charge Density (pH 7.0) -0.0641

GRAVY Index-0.20

Hydrophobic Moment 0.45

Boman Index0.07

Instability Index50.02

Aliphatic Index 84.91

Aromaticity 0.0727

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2405.26

LogP -16.90

H-bond Donors 83.0

H-bond Acceptors 86.0

Rotatable Bonds 208.0

Heavy Atoms 432.0

Ring Count 9.0

Amide Bonds 58.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0257350 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus cereus VD021 [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence