Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length92 amino acids

Chemical FormulaC449H698N130O126S8

DescriptionStandard

        MKFFVLVAIAFALLACVAQAQPVSDVDPIPEDHVLVHEDAHQEVLQHSRQKRATCDLLSKWNWNHTACAGHCIAKGFKGGYCNDKAVCVCRN
    

Molecular Weight10189.66 Da

Isoelectric Point (pI)6.98

Net Charge (pH 7.0)-0.04

Net Charge (pH 7.4) -0.68

Charge Density (pH 7.0) -0.0004

GRAVY Index0.02

Hydrophobic Moment 0.54

Boman Index0.07

Instability Index38.75

Aliphatic Index 86.96

Aromaticity 0.0761

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4075.42

LogP -38.18

H-bond Donors 144.0

H-bond Acceptors 140.0

Rotatable Bonds 331.0

Heavy Atoms 713.0

Ring Count 18.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0216075 VERIFIED: YES

Provenance & Taxonomy

OrganismDrosophila melanogaster [Animal]

FamilyDefensin

Tax ID7227

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Anti-Gram-positive Hemolytic

TargetGram Positive Bacteria